BioMarin Pharmaceutical formulates and markets therapies for people with severe and life-threatening rare diseases and medical ailments. LIMIT THE USE OF MY SENSITIVE PERSONAL INFORMATION, POOLED INVESTMENT FUND: OTHER INVESTMENT FUND. The current minimum investment for Baker Brothers Life Sciences, L.P. is $40000000. BeiGene Limited (BGNE): The large (top three) 18.60% BGNE stake has been in the portfolio since their US listing in Q1 2016. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. Unlike many biotech companies, which are pre-revenue, Incyte has been growing its top and bottom line for years. Shares started trading at ~$20 and currently goes for $14.36. the Investor pursuant to the Purchase Agreement, or such number of shares of Common Stock (whether voting or non-voting) issued upon conversion of such number of shares of Series C Preferred (in either case, Section2(c), during the period beginning at the closing of the IPO until such time as the. This website is using a security service to protect itself from online attacks. Instead, they emphasize that focusing on specific companies, which they can analyze and understand deeply and place concentrated positions in their securities, can generate superior returns over the long term. To ensure our website performs well for all users, the SEC monitors the frequency of requests for SEC.gov content to ensure automated searches do not impact the ability of others to access SEC.gov content. The below charts are illustrative of the type of graphical data available to our clients and do not represent live data. this Agreement, to the jurisdiction of the courts of the United States located in the State of Delaware or in any Delaware state court and consent that any such action or proceeding may be brought in such courts and waive any objection that they may Unlike top-down investing, which suggests studying the bigger picture of economic factors to make investment decisions, bottom-up investing involves looking at the company-specific fundamentals. The parties agree to use their best efforts and act in good faith in carrying out Investor and its Affiliates, collectively, no longer beneficially own the Required Shares, the Company shall invite a designee of the Investor (the Observer) to attend all These fundamental metrics include business financials, cash flows, and the merit of its goods and services. The Company shall notify the Investor of any objection to an Investor Designee pursuant to this Section2(b) sufficiently in advance of the date (c)Subject at all times to Section3(n) below and the other limitations set forth in this Administrator(s): SS&C Fund Services (Cayman) Ltd, , Rank: 58 out of 30967 registered private funds, Rank: 428 out of 30967 registered private funds, Rank: 7711 out of 30967 registered private funds. These cookies track visitors across websites and collect information to provide customized ads. Over the years, the firm had a number of home runs as the invested firms got acquired at huge premiums. Founded in 2000 by Julian and Felix Baker, Baker Bros. Advisors is a private hedge fund based out of New York City. executed questionnaire in the form that the Company provides to its outside directors generally. PitchBook can help you gauge a funds performance based on IRR, cash flow multiples (DPI, RVPI and TVPI), distributions and more. No delay or omission to Prelude Therapeutics (PRLD): PRLD is a 1.39% of the portfolio position. (1)person designated at any time and from time to time by the Investor (the Investor Designee); provided that, the Company shall have no obligation to support the nomination of or cause the Board of Directors to include in Get the full list, Morningstar Institutional Equity Research. Click to reveal Baker Brothers Life Sciences LP. The firm typically provides services to university endowments, foundations, and families. individual as a nominee to the Board of Directors if a majority of the disinterested members of the Board of Directors reasonably and in good faith determines, after consultation with the Companys outside legal counsel and upon written advice In . Terms of Submission (g)Delays or Omissions. It is based on Baker Brothers regulatory 13F Form filed on 11/15/2021. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. Note: Baker Brothers has significant ownership stakes in the following businesses Aeglea BioTherapeutics (AGLE), Immunocore (IMCR), Kystal Biotech (KRYS), Mereo BioPharma (MREO), Neoleukin Therapeutics, Opthea Ltd. (OPT), Otonomy (OTC:OTIC), Rhythm Pharma (RYTM), Talis Biomedical (TLIS), Verastem (VSTM), and Zymeworks. Angel, Fund of Funds, Venture Capital), This describes the stage of investments made by this organization (e.g. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Fund structure AUM Fund type; Baker Brothers Investments: $25.71 bn: 667, L.P. $2.27 bn: Hedge Fund: Baker Brothers Life Sciences, L.P. $23.42 bn: Hedge Fund: Hcif Offshore LP: Latest filings (excl ownership) We're built to manage the complete launch and commercialization of products or address specific program or patient needs. Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on [] Recession Risk Determine whether Baker Brothers Life Sciences grew or shrank during the last recession. The Ascendis stake was increased this quarter while decreasing Amarin and dropping Apellis Pharma. Performance over the past three years has lagged, but it could be a temporary phase for the fund, which, after all, focuses on long-term returns. Kodiak Sciences (KOD): KOD is a large (top five) ~6% of the portfolio position. Management owns 12 percent of the fund. See how we calculate 13F filing performance here. EPS over the medium-term is expected to grow by around 30% since Incyte is an industry leader, having essentially monopolized its areas of treatment. After giving effect to the transactions reported herein and as a result of their ownership interest in Baker Brothers Life Sciences Capital (GP), LLC, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in the Issuer's shares of Common Stock reported in column 5 of Table I directly held by Baker Brothers . We also use third-party cookies that help us analyze and understand how you use this website. Data constructed from Baker Brothers 13F filings for Q2 2021 and Q3 2021. ACADIA Pharmaceuticals (ACAD): The ~3% ACAD stake was established in the 2012-2013 timeframe at very low prices. You can also sign up for email updates on the SEC open data program, including best practices that make it more efficient to download data, and SEC.gov enhancements that may impact scripted downloading processes. It is the funds second-largest holding, occupying 14.9% of its total portfolio. 13F filing from Baker Brothers Life Sciences LP, enter your The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". 1001 and 1030). Note: Baker Brothers controls ~10% of BioCryst Pharmaceuticals. Disclosure: I/we have a beneficial long position in the shares of ACAD, BMRN, INCY either through stock ownership, options, or other derivatives. It does not store any personal data. The stock currently trades at $71.81. Its stake in Seattle Genetics is up $1 billion since news of. The stock currently trades at $3.46. Note:Do to a changed CUSIP number, Baker Brothers holding Evofem Biosiences (EVFM) is not in the spreadsheet. Linda Rosenberg Ach P '12. A privately owned hedge fund sponsor. In the event of any change in the capitalization of the Company, as a result of any stocksplit, stock dividend or stock combination or otherwise, Despite a losing win-record, the firm has managed to post outstanding returns through prudent position. 12b-2 under the Securities Exchange Act of 1934, as amended. Please visit our Tracking Baker Brothers Portfolio series to get an idea of their investment philosophy and our previous update the funds moves during Q2 2021. Baker Bros. Advisors LP 860 Washington Street, 3 rd Floor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) October 11, 2019 (Date of event which requires filing of this statement) Baker Brothers stake goes back to funding rounds prior to the IPO. the provisions of this Agreement shall be appropriately adjusted. The parties The bottom line has never been positive, however, with losses persisting even as sales are growing. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. However, most of them comprise risky pre-revenue firms that should only be considered upon having a great understanding of their business model. Form D is a form to be used to file a notice of an exempt offering of securities with the Securities and Exchange Commission. Once the rate of requests has dropped below the threshold for 10 minutes, the user may resume accessing content on SEC.gov. Shares plunged by a massive 45%, and they have yet to recover since then. Employees: 2,680 21823 30TH DRIVE SE, SUITE, BOTHELL, WA, 98021 4255274000 seagen.com Seagen Inc. develops and commercializes therapies for the treatment of cancer in the United States and internationally. There are 20 positions that are significantly large (more than 0.5% of the portfolio each) and they are the focus of this article. enable the Investor to propose a replacement Investor Designee in accordance with the terms of this Agreement. Baker Brothers Life Sciences Capital, L.P. is entitled to a performance allocation under the Issuer's organizational documents. Q3 2015 saw a ~30% stake increase at prices between ~$105 and ~$130. Please send any feedback, corrections, or questions to support@suredividend.com. Pour plus dinformations, veuillez consulter notre politique de gestion des cookies. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The current minimum investment for Baker Brothers Life Sciences, L.P. is $40000000. Our clients include: large branded pharmaceutical companies established and emerging biotechnology companies international medical devices companies food and beverage companies They add up to ~73% of the portfolio. Ascendis Pharma A/S (ASND): The bulk of the current ~3% of the portfolio stake in ASND was built in 2017 at prices between ~$20 and ~$40. For the Baker Bros. -- the biggest shareholder in both companies -- the value of its investments have soared by about $1.4 billion. Current guidelines limit users to a total of no more than 10 requests per second, regardless of the number of machines used to submit requests. To ensure this doesnt happen in the future, please enable Javascript and cookies in your browser. value remained steady this quarter at $22.77B. Baker Brothers Life Sciences is a 2006 vintage buyout fund managed by Baker Brothers Investments. The stock currently trades at ~$153. Industry: Pooled Investment Fund (See others in industry) Address: 860 Washington Street 3 Rd Floor. Mr. Goller serves as a Partner of Baker Brothers Investments, a fund management company focused on long-term investments in life-sciences companies. This is quite odd since the company is based in Beijing, China, which means that the funds due diligence process has to go to the next level due to the weaker Chinese reporting standards. Signature and Submission Please verify the information you have entered and review the Terms of Submission below before signing and clicking SUBMIT below to file this notice. time, and particular provisions of this Agreement may be waived or modified, with and only with an agreement or consent in writing signed by the Company and the Investor. This website uses cookies to improve your experience. You can email the site owner to let them know you were blocked. Since then the activity has been minor. Last major activity in MRTX was a ~50% selling in Q3 2019 at prices between ~$76 and ~$106. or to simply have an email sent to you whenever we receive a new The stock currently trades at ~$344 and the stake is at 1.48% of the portfolio. Baker Brothers Life Sciences, L.P. is a hedge fund operated by Baker Brothers Investments and has approximately $13.9 billion in assets. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. Reference ID: 0.bfed655f.1677703966.7fc99eb. By: /s/ Scott Lessing You can adjust your settings for these cookies and other trackers via this cookie banner. All rights reserved. Baker Brothers Life Sciences LP; Firm: Fund # CIK # 0001363364: Sale: Fund: Phone: 2123395633: Address: 667 Madison Avenue New York, New York 10065: Source This is a profile preview from the PitchBook Platform. (d)Successors and Assigns. Nominating Agreement as of the date first above written. This Agreement, the Bylaws and 33. The stock currently trades at $13.72. The position was left unchanged during the previous quarter. The fund is located in New York, New York and will invest in United States. While the company has continued to grow, the business seems incapable of meeting investors past expectations. Shares started trading at ~$24 and currently goes for ~$246. These investors may include private investors, venture capital firms, or other investment vehicles. I am not receiving compensation for it (other than from Seeking Alpha). expressly agree that the provisions of this Agreement may be specifically enforced against each of the parties hereto in any court of competent jurisdiction. (m)Enforcement. All rights reserved. Baker Brothers Life Sciences Capital (GP) LLC New York, New York BlueMountain Capital Management Investment Management New York, NY . benefit of, and be binding upon, the successors, assigns, heirs, executors, and administrators of the parties hereto. the slate of nominees recommended to the Companys stockholders for election as directors of the Company an Investor Designee if the Investor already has at least one Investor Designee serving as a director on the Board of Directors at the time Lists Featuring This Company Early Stage Venture Investors (Top 10K) 10,000 Number of Organizations $63B Total Funding Amount 1,945 Number of Investors Track Private New York Companies (Top 10K) The parties expressly agree that the provisions of this Agreement may be They have a ~29% ownership stake in the business. H1 2018 saw the stake built from ~3.8M shares to ~12M shares at prices between ~$100 and ~$215. Baker Bros. Advisors LP 860 Washington Street, 3rdFloor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) January 12, 2023 (Date of event which requires filing of this statement) If the filing person has previously filed a statement on Schedule other electronic means), each of which may be executed by less than all of the parties hereto, each of which shall be enforceable against the parties actually executing such counterparts, and all of which together shall constitute one instrument. exercise any right, power or remedy accruing to the Investor hereto upon any breach or default of the Company under this Agreement, shall impair any such right, power or remedy of the Investor nor shall it be construed to be a waiver of any such Shares started trading at ~$49 and currently goes for $13.27. The stock is now well below that range at $9.78. For best practices on efficiently downloading information from SEC.gov, including the latest EDGAR filings, visit sec.gov/developer. Felix Baker '91, PhD '98. President, Rosenberg Ach Foundation. The life sciences sector is changing by the minute. The stock is now at $87.22, and the stake is at 2.59% of the portfolio. under clause (c)or (d); (c) by prepaid certified or registered mail, return receipt requested;or (d)by prepaid reputable overnight delivery service. Madrigal Pharmaceuticals (MDGL) and Mirati Therapeutics (MRTX): These two small (less than ~1.10% of the portfolio each) stakes were kept steady this quarter. The position was rebuilt in Q3 2019 at prices between ~$18.50 and ~$27. I have no business relationship with any company whose stock is mentioned in this article. Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. There are 20 positions that are significantly large (more than 0.5% of the portfolio each) and they are the focus of this article. The cookie is used to store the user consent for the cookies in the category "Other. closing of the IPO and for three (3)years thereafter, at any time at which the Investor and its Affiliates, collectively, beneficially own (i)the Required Shares and (ii)at least 2% of the Companys then-outstanding voting AND RESTATED NOMINATING AGREEMENT]. Whalewisdom has at least 2 Form 4 filings The firm last filed a Form D notice of exempt offering of securities on 2022-07-01. Recent M&A winners include Pharmacyclics (acquired by AbbVie), Synageva (acquired by Alexion), Salix (acquired by Valeant), and Alexion (acquired by AstraZeneca). This quarter saw a marginal increase. For more information, contact opendata@sec.gov. San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. If any provision of this Agreement shall be invalid, illegal or unenforceable, the As Chicago's biotech ecosystem continues to expand . Si vous y consentez, nous et nos partenaires utiliserons galement des cookies et autres traceurs de mesure daudience, de publicit et de rseaux sociaux, dont le dtail des finalits est accessible depuis le bouton Grer les paramtres . The firm primarily invests in life science companies. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. The fund has grown rapidly over the years due to its extraordinary returns and currently boasts approximately $15.2 billion of assets under management (AUM). IN WITNESS WHEREOF, each of the parties hereto has executed this Amended and Restated
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