My pup is scheduled to see a neurologist Monday ( today's friday) to evaluate. This is worth the cost to buy a six-pack of protection. I have always been apprehensive about putting my dog on Heartworm / Flea Tick medication because of horror stories, but I thought he's 5 and it will be from the vet and it seems like the responsible thing to do. These are classic neurological symptoms, exactly what our Pickles had before she passed. Simparica can cause ataxia, which is the official name for loss of body control. On 01/07/21, we gave our 11 year old black lab, Rawley, a 2nd dose of Simparico TRIO. I started thinking about his history. She said to watch for drainage. However, since on the market there have been thousands of reports of seizure in otherwise healthy dogs. Simparica has caused my 12 pound 5 year old Jack Russel Terrior mix to have leg tremors and have trouble walking, jumping, or running. She has episodes where she seems very anxious and is hiding under car/tables/beds. My 1.5 yr old German Shepherd was a happy, playful healthy dog until this Poison and now I blame myself for what she is going through. This time he is having seizures. - she's had several episodes since then. She didn't make it to the next day and died overnight. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. I dont know whether its a coincidence or not, but 4 days after second dose of Simparica Trio, my dog ended up at an urgent care with blood in his urine. Will it get worse Will he get better? Mine has tremors once in a while and now I know why! I will use Sentinel and Pet Armor on her as this is what I have always gjven my dogs with no problems. If your dog has reactions to this medicine, push fluids! Will not be using this treatment again!!! Now, here we are one month later and I just gave him the second dose about two hours ago. I am sure simparica caused a fatal seizure in my boxer. Once she is completely healed I am putting her back on those. Exactly. Vet trip and meds $400! Would appreciate any opinion you all may have. Called vet and was advised chicken and rice by tech - vet did not come to the phone even tho I asked to speak to her twice. I am so mad at myself and so upset that I am the one that has made him sick. After realizing that the only thing that we did differently was to give him his first dose of Simperica, my wife began research and came across this conversation. We go for more bloodwork today and are praying for better news. It's definitely not! . Later in the fall I noticed some leg tremors when she squatted. If she comes out of this I will return to heartworm pills and topical flea and tick meds. Another one of our dogs also has had several episodes of suddenly crying as if she is in great pain and also began within a week of administering the poison (please don't call this a medicine, it is a poison intended to kill fleas and other bugs and in this case it can also kill your doggie). I have noticed that he hardly needs no meds for this neurological issue near the end of the month. Update on my Labradoodle who started seizures just a few hours after receiving first dose of Simparica on T-Day 2020 it is March 2021 and my Vet put my dog on Phenobarbital for anti-seizure med. This happened to our 2yr old frenchie last Friday. He has been using Simparica Trio since it came out several years ago, which eliminates the need for an additional monthly heart guard chewable. He lays on his bed tucked far in the corner. I would find another vet for a second opinion. He could not hold down any food or water. They both got similar issues and this was the only thing they both did. Lethargic and confused. So I did. I am also very worried about him. Gave Simparica to my dog yesterday. I thought the first one it happened to may have gotten something in her eye but then a few days later the other had the same issue. So no Addisions. As per chewable tablets, this medicine is safe for all breeds of dogs. The following list includes the known side effects of Simparica. I have been telling everyone not to give this to their furry ones!!!!!!!! Now Im scared ive been giving him Simparica Trio and it could be the cause of his progressively worsening sickness. In general dogs tolerate very well sarolaner at the therapeutic dose range (2 to 4 mg/kg). How can it not be the Simparica that did this to my baby when nothing else changed. About 2 weeks later he had tremors, drooling, lethargic, uncoordinated, vomiting and was touch and go for a couple days. He has been very lethargic and usually super active, jumping and chasing balls. Then I saw this and realized. The only thing in his diet that really changed was his flea, tick and heartworm protection. He also lashes at me with his teeth. I gave it to her then I looked at the box that said never tested on pregnant dogs . So from what I understand, your dog was on this for 6 months and got the serious symptoms after that? Our vet pushed this new drug for this tick season claiming the drug we used previously they had 11 dogs in the previous year were diagnosed with Lyme disease and they no longer had confidence in that drug. I am feeding her foods such as spirulina; b12 and a special healing earth in her dinner. Simparica is available by prescription only, so discuss any history your dog has of seizure disorders with your veterinarian when determining the best flea and tick treatment for your pet. My 3 month old shih tux Juno took her second dose last week and for the last two days shes vomited and has been eating grass nonstop! We took him to vet and they gave nausea meds and kept him overnight. PROS Treats adult fleas and prevents flea and tick infestations Effective against five types of tick Liver flavored tablet FDA Approved CONS The flavored, chewable tablets were consumed . My vets comment was I would know if his symptoms were related if at time for next dose his symptoms were gone they are gone. Any response from the company? I called the breeder, and she said some vaccines and heartworm meds can cause neurological issues. My vet recommended this for my puppy, he is now lethargic, has blood in stool, and can hardly stay awake. Shes not the carefree setter she was prior to this medication. Customer: Took a dose of simparica trio.second rose in second month.dog is having tremors JA: I'll do all I can to help. Gave this flea medicine today and by 10 pm toy poodle having siesures every 3-10 seconds. I'm besides myself. Has anyones dog stopped having seizures when the medication wore off or is this going to be a permanent issue possibly getting worse? Sarolaner is effective against the following tick species: Moxidectin is an antiparasitic drug in the macrocyclic lactone class. The vet said the simparica didn't cause the disease but it could have been the link that pushed him into the Crisis. 12/18/21.. he did experience some diarrhea. Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. My poor puppy has to go under anesthesia on top of. Sarolaner is also used in combination products for both dogs and cats. Our guy is having pain and is showing arthritic symptoms. It went away, I thought the diarrhea was from some of the junk she eats off of the ground. The only change I could think of he started taking Simparica about 4 months ago. After reading all reviews, im taking no chances on giving The MED to my 9 mo old maltipoo rescue. Simparica Trio is intended for dogs and puppies weighing more than 2.8 pounds and older than 8 weeks of age. Simparica is good at killing contagious parasites that cause mange and scabies. Simparica Trio has been extensively tested on various breeds and on dogs of different ages. Which Type of Dog Fence Is Right For Your Pet? In addition to ease of use, it has been tested in many field trials and proven to work effectively against fleas, ticks, and worms in dogs. All oral tick meds are a risk. He was a normal dog before the medicine Simpatico Trio . old . Can you tell me if your dog is back to normal now?!?! If fact it specifically states on the product label "Not for use in humans". No side effects. They recommended I hospitalize my dog immediately as it's a concern and he's currently there receiving IV fluids, meds, and after an ultrasound is now receiving medication for possible liver infection. I won't sleep until we all get the justice for our babies that don't have voices of their own. I understand them charging for the Euthanasia and cremation but they said they would keep her for 12 hours and she was put down at around 3:00 which was 1/2 the time they agreed on.Now he will get none of the fees back that the company offered for the dogs care, and hey don't have their dog .On top of that they have 3,500.00 vet bills.Why are vets allowed to charge so much?it is more than a person.It really seems as though they don't care about the pets or the people that own them Also why is these types of flea meds still on the market and why is there no legal action available for the poor consumers.I feel like they were legally assaulted by all involved and let us not forget the poor 2 year old rescue dog who ended up having a terrible short life.How unfair. I have noticed that recently he seems to stumble a little from time-to-time. It was a mistake using this and I hope that in 4 weeks when it is out of her system, she will return to normal. I put him on boiled chicken & rice and got him calmed down. Simparica Trio can be administered to your dog at any age, but it's best to start treating your dog one month before the fleas become active. I have another dog, but gave him Frontline and he's fine. Sarah thanks for your response! I will never use this product again!!!!! We started the medication on Dec. 1st and 3 days later it started with vomiting and loss of appetite. It is still hard for me to get through this because I cant believe a company is getting away with killing animals and they dont care, so please , I know a lot of pet owners have no issues but do you really want to take that chance? Hi, how long it took for the diarrhea to go away. I lost my dog due to Simparica Trio. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a . He seems to be out of sorts, staring into space, getting freaked out when he can't see me (I thought he was losing his eyesight). He has all the symptoms Eveyone is describing. gave this to my dog three different times. This is still going on weeks later. Got home 4 hours later and my dog fell down three times and is now seizing mainly her head . So if your dog actually has meningitis then that wouldn't be related to having given him Simparico but a separate matter altogether. I did not notice any side effects. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. Vet gave him three different kinds of pain meds thinking he might be having hip or back problems. I sure hope we don't have ongoing problems. Then the following week 1 pill every other day . Omg this is horrible. Not even going to risk it . Side effects include: vomiting, diarrhea, lethargy, anorexia, otitis externa (ear. Overly anxious. In our case the damage was permanent. Heal quickly and clumps of hair fall out. HELP!! Sorry man, that is horrible. He is my first dog, he is 5yrs old now, and this is all new. That trip cost $400 and the result was he needed Simparica flea treatment. She has NEVER done that before. I threw him his ball and he actually was interested in it. Doing better now, 2 days later. If undiagnosed he would have died. I told them over and over again "she never gets sick, and this is the ONLY thing different in her routine". Simparica Trio is the first and only product that combines sarolaner, moxidectin, and pyrantel in one simple-to-give chewablefor protection against: . Moxidectin stops heartworm . This seemed like perfect treatment 3 in 1 but at what cost? My lab puppies have been taking Simparica Trio for 2 months. Why would he knowingly recommend this? If this is a long term issue, I doubt they would be willing to cover all visits in the future. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The diarrhea and vomiting went away after a few days but the cough has lingered for over a month now even with treatment. How can they put something that can cause this level of damage on the market and how do vets not even tell us to monitor our pets or tell us what the risks are. Last year I gave them this but didn't notice any issues. We gave our one year old Simparica tonight and he started having trimmers that lasted on and off for about 30 minutes. (145 Reviews) $15.50 - $31.09. Moxidectin was first approved by the FDA in 1997 for the prevention of heartworm disease in dogs. Eight hours later and she has terrible diarrhea and vomiting, now she is not eating. She seems more anxious now and really attached to hubby. I just gave him heartgard and nexgard about 2 weeks with no issues. I fell like hes dying right before my hands. 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